USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: GDIR2_HUMAN USC-OGP 2-DE database:  GDIR2_HUMAN GDIR2_HUMAN General information about the entry View entry in simple text format Entry name GDIR2_HUMAN Primary accession number P52566 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Rho GDP-dissociation inhibitor 2; Short=Rho GDI 2; AltName: Full=Ly-GDI {ECO:0000303|PubMed:8356058}; AltName: Full=Rho-GDI beta;. Gene name Name=ARHGDIB Synonyms=GDIA2, GDID4, RAP1GN1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0199: pI=5.04; Mw=24929 PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0527: pI=5.06; Mw=25070 SPOT OGP-0533: pI=5.13; Mw=24290 SPOT OGP-0534: pI=5.06; Mw=24205 SPOT OGP-0536: pI=5.09; Mw=24120 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0807: pI=5.12; Mw=25977 SPOT OGP-0814: pI=5.13; Mw=24261 SPOT OGP-0816: pI=5.03; Mw=24111 SPOT OGP-0817: pI=5.10; Mw=24111 SPOT OGP-0820: pI=5.11; Mw=23910 SPOT OGP-0826: pI=5.06; Mw=23121 SPOT OGP-0831: pI=5.06; Mw=22452 Cross-references UniProtKB/Swiss-Prot P52566; GDIR2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GDIR2_HUMAN Primary accession number P52566 Secondary accession number(s) B5BU79 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 164) Name and origin of the protein Description RecName: Full=Rho GDP-dissociation inhibitor 2; Short=Rho GDI 2; AltName: Full=Ly-GDI {ECO:0000303|PubMed:8356058}; AltName: Full=Rho-GDI beta; Gene name Name=ARHGDIB Synonyms=GDIA2, GDID4, RAP1GN1 Encoded on Name=ARHGDIB; Synonyms=GDIA2, GDID4, RAP1GN1 Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; GTPase activation; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L20688; AAA59539.1; -; mRNA EMBL X69549; CAA49280.1; -; mRNA EMBL L07916; -; NOT_ANNOTATED_CDS; mRNA EMBL AF498927; AAM21075.1; -; mRNA EMBL AB451315; BAG70129.1; -; mRNA EMBL AB451445; BAG70259.1; -; mRNA EMBL CH471094; EAW96336.1; -; Genomic_DNA EMBL BC009200; AAH09200.1; -; mRNA CCDS CCDS8671.1; -; . PIR A47742; A47742; . RefSeq NP_001166.3; NM_001175.6; . RefSeq NP_001308349.1; NM_001321420.1; . RefSeq NP_001308350.1; NM_001321421.1; . RefSeq NP_001308351.1; NM_001321422.1; . RefSeq NP_001308352.1; NM_001321423.1; . UniGene Hs.504877; -; . PDB 1DS6; X-ray; 2.35 A; B=23-199 PDB 5H1D; X-ray; 1.49 A; A=61-201 PDBsum 1DS6; -; . PDBsum 5H1D; -; . ProteinModelPortal P52566; -; . SMR P52566; -; . BioGrid 106890; 14; . DIP DIP-40959N; -; . IntAct P52566; 8; . MINT MINT-1616342; -; . STRING 9606.ENSP00000228945; -; . iPTMnet P52566; -; . PhosphoSitePlus P52566; -; . SwissPalm P52566; -; . BioMuta ARHGDIB; -; . OGP P52566; -; . SWISS-2DPAGE P52566; -; . EPD P52566; -; . MaxQB P52566; -; . PaxDb P52566; -; . PeptideAtlas P52566; -; . PRIDE P52566; -; . TopDownProteomics P52566; -; . DNASU 397; -; . Ensembl ENST00000228945; ENSP00000228945; ENSG00000111348; . Ensembl ENST00000541546; ENSP00000440560; ENSG00000111348; . Ensembl ENST00000541644; ENSP00000444860; ENSG00000111348; . GeneID 397; -; . KEGG hsa:397; -; . UCSC uc001rcq.2; human; . CTD 397; -; . DisGeNET 397; -; . GeneCards ARHGDIB; -; . H-InvDB HIX0036989; -; . HGNC HGNC:679; ARHGDIB; . HPA CAB018584; -; . HPA HPA051235; -; . MIM 602843; gene; . neXtProt NX_P52566; -; . OpenTargets ENSG00000111348; -; . PharmGKB PA24964; -; . eggNOG KOG3205; Eukaryota; . eggNOG ENOG4111K44; LUCA; . GeneTree ENSGT00390000006233; -; . HOGENOM HOG000175765; -; . HOVERGEN HBG000206; -; . InParanoid P52566; -; . KO K12462; -; . OMA QDHLTWE; -; . OrthoDB EOG091G0MBU; -; . PhylomeDB P52566; -; . TreeFam TF105387; -; . Reactome R-HSA-194840; Rho GTPase cycle; . SIGNOR P52566; -; . ChiTaRS ARHGDIB; human; . EvolutionaryTrace P52566; -; . GeneWiki ARHGDIB; -; . GenomeRNAi 397; -; . PMAP-CutDB P52566; -; . PRO PR:P52566; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000111348; -; . CleanEx HS_ARHGDIB; -; . ExpressionAtlas P52566; baseline and differential; . Genevisible P52566; HS; . GO GO:0005737; C:cytoplasm; TAS:UniProtKB; . GO GO:0031410; C:cytoplasmic vesicle; TAS:ProtInc; . GO GO:0005856; C:cytoskeleton; TAS:UniProtKB; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016020; C:membrane; IEA:Ensembl; . GO GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW; . GO GO:0003924; F:GTPase activity; IMP:CACAO; . GO GO:0048365; F:Rac GTPase binding; IDA:UniProtKB; . GO GO:0005094; F:Rho GDP-dissociation inhibitor activity; IDA:UniProtKB; . GO GO:0071461; P:cellular response to redox state; IEA:Ensembl; . GO GO:0006928; P:movement of cell or subcellular component; TAS:UniProtKB; . GO GO:0007275; P:multicellular organism development; TAS:ProtInc; . GO GO:0007162; P:negative regulation of cell adhesion; TAS:ProtInc; . GO GO:1901164; P:negative regulation of trophoblast cell migration; IDA:CACAO; . GO GO:2000249; P:regulation of actin cytoskeleton reorganization; IMP:UniProtKB; . GO GO:0035023; P:regulation of Rho protein signal transduction; IDA:UniProtKB; . GO GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome; . Gene3D 2.70.50.30; -; 1; . InterPro IPR014756; Ig_E-set; . InterPro IPR000406; Rho_GDI; . InterPro IPR024792; RhoGDI_domain; . PANTHER PTHR10980; PTHR10980; 1; . Pfam PF02115; Rho_GDI; 1; . PRINTS PR00492; RHOGDI; . SUPFAM SSF81296; SSF81296; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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